This section provides an overview of the main steps involved in a crystallographic fragment screening campaign at FragMAX. Users can choose how closely they would like to be involved in the experimental work. At a minimum, this typically involves providing protein and reagents at the beginning of the project and carrying out structure refinement and analysis at the end. The flowchart below outlines the flow of a FragMAX screening project. The individual steps are described in more detail in the following sections.

Fragmax workflow cartoon

The FragMAX workflow from protein to structure.