Illustration of four protein helixes coupled together

Scientists succeed in soaking protein guests into host crystals – a major step towards solving guest structures

A group of researchers have successfully soaked proteins into large protein crystals, marking a hitherto never reported achievement. The X-ray diffraction data, which were collected on MAX IV’s BioMAX beamline, indicate that the guest proteins could follow at least some of the hosts’ structures signifying a so far unparalleled step towards using crystallographic methods to solve guest protein structures. Such insights could pave the way for major advances in biotechnology, material science, and structural studies.

Highlights

Drone image of MAX IV from above, surrounded by green landscape and the horizon.

A record year for research at MAX IV

MAX IV is making significant societal contributions in terms of record-high scientific productivity. In 2023, the number of publications increased by 51% compared to the previous year, and the number of unique users increased by 31%. Moreover, the number of proposals submitted in the most recent Open Call was higher than ever.

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Conceptual design for three potential new beamlines developed with WISE

After successfully bringing the first 16 funded beamlines into operation, we now look into the future. In collaboration with the Wallenberg Initiative Materials Science for Sustainability (WISE), funded by the Knut and Alice Wallenberg Foundation and together with the scientific community, MAX IV will develop the conceptual designs for three potential new materials science beamlines.