The innovative project “Acoustofluidic Crystallography” (AFX) is set to revolutionize the field of serial crystallography (SX) by introducing a novel sample delivery method that promises to enhance the efficiency and reliability of experiments conducted at synchrotrons and X-ray free-electron lasers (XFELs). This cutting-edge research is a collaborative effort involving KTH Royal Institute of Technology, DESY, and MAX IV, funded by the LEAPS-INNOV initiative (GA: 101004728).
Kilohertz serial crystallography to film nature’s choreography
A collaborative work between MAX IV and Paul Scherrer Institute researchers investigated a setup to conduct serial and time-resolved macromolecular crystallography at MAX IV. The experiment shows that the setup, based on JUNGFRAU detector and Jungfraujoch data-acquisition system, can provide a molecular moving picture of up to 500 microseconds in resolution of protein dynamics – providing ten times finer details than the previously available method. The setup is in the works to be made available at MicroMAX beamline.
One step towards prevention of diabetes linked substance produced by the human gut microbiota – first user experiment at MicroMAX
The team at the Novo Nordisk Foundation funded life science beamline MicroMAX welcomed the first users in December 2023. In the experiment the users investigated an enzyme that may be found in some bacteria of human gut microbiota and may have a role in the development of diabetes and other diseases.