MicroMAX exterior

MicroMAX will open up new possibilities in the area of structural biology making it possible to study proteins in 3D and to follow them in time. MicroMAX will allow studying the molecules that are most interesting but most difficult to study because they only provide microcrystals. This will be achieved by providing a very small but parallel and intense X-ray beam and by making it possible to use new methods of presenting the samples to the X-ray beam. The technique used is called X-ray crystallography: by making crystals of the protein molecules, shine our X-ray beam on the crystals and record the scattered X-rays it is possible to obtain a 3D-model of the protein molecule.

The science of structural biology studies structures of biological molecules with the goal to understand how biology works on a molecular level. The function of these molecules is determined by their structure, and since most functions in for example our cells are carried out by these molecules, it is fundamental to understanding life. X-ray crystallography plays an important role in the development of new medicines.

Call for proposals: Commissioning users summer 2022 – summer 2023

A call for proposal will open February 14 with closing deadline March 14. For more general information about the call see https://www.maxiv.lu.se/users/proposal-calls/.

We invite proposals for commissioning users to help test and develop the functionality of the beamline before it opens for general users. MicroMAX is expected to take first light before or after the summer shutdown 2022. The beamline will then be commissioned with different functionality becoming available during this period, but the exact order and time will depend on the progress.

MicroMAX will open to general users in Q2 2023.

Brief description of the functionality becoming available during the period summer 2022 – summer 2023

During this period the beamline will primarily be operated at fixed energy with some possibility to change energy in its energy range 5 – 25 keV. Both monochromators will be commissioned (narrow bandwidth and wide bandwidth / “pink beam”) but the flux of the multilayer beam might be limited compared to the final flux (1014 – 1015 photons/s). The focused beam size is expected to be down to 5 μm but the final focus of 1 μm will become available after this period. The end station will be equipped with an MD3-UP diffractometer, an Isara sample changer and an Eiger2 X 9M CdTe photon-counting detector. Rotational crystallography with monochromatic beam assisted by the sample changer and controlled by MXCuBE will be commissioned. Serial crystallography will also be commissioned during this period, both fixed target and injector based.
For the commissioning beamtime the following equipment is planned to be taken in operation: Crystal & multilayer monochromators, CRL focusing down to 5 μm, Photon-counting area detector

MicroMAX will open to general users in Q2 2023.

MicroMAX has been funded by the Novo Nordisk Foundation.

Contact Info: Thomas Ursby

Techniques

Available forTechnique description
Commissioning ExpertsRotational crystallography, monochromatic beam, fixed energy, sample changer
Commissioning ExpertsSerial crystallography - fixed target and injector, monochromatic or wide bandwidth (0.3%; 1%)